Collect. Czech. Chem. Commun. 2006, 71, 978-990
https://doi.org/10.1135/cccc20060978

Microwave-Assisted Synthesis of Fluoroquinolones and Their Nucleosides as Inhibitors of HIV Integrase

Martina M. Adamsa, Jan W. Batsa, Nadja V. Nikolausa, Myriam Witvrouwb, Zeger Debyserb and Joachim W. Engelsa,*

a Institute for Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-University, Marie-Curie-Str. 11, 60439 Frankfurt am Main, Germany
b Molecular Medicine, Katholieke Universiteit Leuven and IRC Kulak, Kapucijnenvoer 33, B-3000 Leuven, Flanders, Belgium

Individual author index pages


Other CCCC articles of these authors

  • Thomas J. Lehmann, Karin Schwarzer, Markus Schweitzer and Joachim W. Engels
    Thermodynamic and CD-spectroscopic characterization of self-complementary methyl- and benzyl-modified d(CGCpGCG)-hexamers
    Symposium Series 1999, Vol. 2, pp. 302–305 [Abstract]
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  • Thorsten Strube and Joachim W. Engels
    Synthesis and thermodynamic properties of different 2'-fluoro modified UUCG hairpin loops
    Symposium Series 1999, Vol. 2, pp. 298–301 [Abstract]
    Published online 2016-05-08 23:33:16
  • Uwe Parsch and Joachim W. Engels
    Calculation of thermodynamic data from UV melting curves of triple helical nucleic acids: A comparison of methods
    Symposium Series 1999, Vol. 2, pp. 15–21 [Abstract]
    Published online 2016-05-08 20:40:02
  • Jörg Parsch and Joachim W. Engels
    C–F···H–C hydrogen bonds in crystals of fluorobenzene ribonucleosides
    Symposium Series 1999, Vol. 2, pp. 11–14 [Abstract]
    Published online 2016-05-08 20:39:56
  • Aleksandra Živković, Jan W. Bats and Joachim W. Engels
    Crystal structures of fluoro- and chloro-modified benzene-nucleosides
    Symposium Series 2002, Vol. 5, pp. 396–398 [Abstract]
    Published online 2016-01-25 20:52:16
  • Nelly Piton, Frédéric Godde and Joachim W. Engels
    Determination of RNA tertiary structure by advanced electron paramagnetic resonance spectroscopy (EPR)
    Symposium Series 2002, Vol. 5, pp. 381–382 [Abstract]
    Published online 2016-01-25 20:51:44
  • Astrid E. Klöpffer and Joachim W. Engels
    Universal fluorinated nucleobases: Their effect on the catalytic activity of ribozymes
    Symposium Series 2002, Vol. 5, pp. 348–351 [Abstract]
    Published online 2016-01-25 20:50:43
  • Kerstin Jahn-Hofmann and Joachim W. Engels
    A new concept for DNA-arrays
    Symposium Series 2002, Vol. 5, pp. 335–337 [Abstract]
    Published online 2016-01-25 20:42:46
  • Joachim W. Engels, Thomas J. Lehmann, Jörg Parsch and Thorsten Strube
    Fluorine substituted DNA and RNA
    Symposium Series 2002, Vol. 5, pp. 245–250 [Abstract]
    Published online 2016-01-25 20:40:52
  • Stefan Amberg and Joachim W. Engels
    Synthesis, properties and determination of the configuration of arylpropyl backbone modified oligodeoxynucleotides
    Symposium Series 2002, Vol. 5, pp. 225–229 [Abstract]
    Published online 2016-01-25 20:40:31
  • Jelena Božilović, Jan W. Bats and Joachim W. Engels
    Synthesis and crystal structures of fluorinated indols as RNA analogues
    Symposium Series 2005, Vol. 7, pp. 385–386 [Abstract]
    Published online 2015-11-08 11:55:55
  • Aleksandra Živković and Joachim W. Engels
    Fluorinated benzenes and benzimidazoles as RNA analogues
    Symposium Series 2005, Vol. 7, pp. 271–275 [Abstract]
    Published online 2015-11-08 11:53:48
  • Gerda Wittel, Ping Gu and Joachim W. Engels
    Synthesis and activity of C-analogues for immune stimulating CpG-oligodeoxynucleotides
    Symposium Series 2005, Vol. 7, pp. 493–494 [Abstract]
    Published online 2015-11-08 11:49:35
  • Lena Wicke and Joachim W. Engels
    Synthesis of 6-substituted quinolone nucleosides as potential HIV integrase inhibitors
    Symposium Series 2008, Vol. 10, pp. 473–475 [Abstract]
    Published online 2015-10-30 18:45:41
  • Angelika Keller and Joachim W. Engels
    Synthesis of 3'-O-cyanoethyl-2'-deoxythymidine-5'-monophosphate and its use for the sequencing-by-synthesis technology
    Symposium Series 2008, Vol. 10, pp. 376–377 [Abstract]
    Published online 2015-10-30 18:42:36
  • Jamal Krim, Bouchra Sillahi, Moha Taourirte, Said Eddarir and Joachim W. Engels*
    Synthesis and antibacterial activity of unsaturated pyrimidine carboacyclonucleoside analogues
    2011, Vol. 76, Issue 11, pp. 1299–1305 [Abstract]
  • Angelika C. Keller*, Saulius Serva, Diana C. Knapp, Marek Kwiatkowski and Joachim W. Engels
    Synthesis of 3′-O-(2-cyanoethyl)-2′-deoxythymidine-5′-phosphate as a model compound for evaluation of cyanoethyl cleavage
    2009, Vol. 74, Issue 4, pp. 515–534 [Abstract]
  • Markus Schweitzer, Wendelin Samstag and Joachim W. Engels
    Synthesis and characteristics of a self-complementary tetramer d(CGCG) with methylphosphonate linkages of defined stereochemistry
    1996, Vol. 61, Special Issue, pp. S213–S216 [Abstract]