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Collect. Czech. Chem. Commun. 2006, 71, 912-928
https://doi.org/10.1135/cccc20060912

Nucleoside Prodrugs of A3 Adenosine Receptor Agonists and Antagonists

Pedro Besadaa, Liaman K. Mamedovaa, Krishnan K. Palaniappana, Zhan-Guo Gaoa, Bhalchandra V. Joshia, Lak Shin Jeongb, Mortimer M. Civanc and Kenneth A. Jacobsona,*

a Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-0810, U.S.A.
b Laboratory of Medicinal Chemistry, College of Pharmacy, Ewha Womans University, Seoul 120-750, Korea
c Departments of Physiology and Medicine, University of Pennsylvania, Philadelphia, PA, U.S.A.

Crossref Cited-by Linking

  • Spinozzi Eleonora, Baldassarri Cecilia, Acquaticci Laura, Del Bello Fabio, Grifantini Mario, Cappellacci Loredana, Riccardo Petrelli: Adenosine receptors as promising targets for the management of ocular diseases. Med Chem Res 2021, 30, 353. <https://doi.org/10.1007/s00044-021-02704-x>
  • Suresh R. Rama, Jain Shanu, Chen Zhoumou, Tosh Dilip K., Ma Yanling, Podszun Maren C., Rotman Yaron, Salvemini Daniela, Jacobson Kenneth A.: Design and in vivo activity of A3 adenosine receptor agonist prodrugs. Purinergic Signalling 2020, 16, 367. <https://doi.org/10.1007/s11302-020-09715-0>
  • Jacobson Kenneth A., Civan Mortimer M.: Ocular Purine Receptors as Drug Targets in the Eye. Journal of Ocular Pharmacology and Therapeutics 2016, 32, 534. <https://doi.org/10.1089/jop.2016.0090>
  • Wang Zhao, Do Chi Wai, Avila Marcel Y., Peterson-Yantorno Kim, Stone Richard A., Gao Zhan-Guo, Joshi Bhalchandra, Besada Pedro, Jeong Lak Shin, Jacobson Kenneth A., Civan Mortimer M.: Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species. Experimental Eye Research 2010, 90, 146. <https://doi.org/10.1016/j.exer.2009.10.001>