Collect. Czech. Chem. Commun. 2006, 71, 832-841

Studies on Oxidative Transformations of Dinucleoside H-Phosphonoselenoates

Martin Bollmarka, Martin Kullberga and Jacek Stawinskib,a,*

a Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, S-106 91 Stockholm, Sweden
b Institute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznan, Poland


The utility of a new type of synthetic intermediates, H-phosphonoselenoate diesters, in the preparation of potentially biologically important nucleotide analogues containing the P-Se bond, was explored by converting dinucleoside H-phosphonoselenoates 1 into various phosphorus(V) derivatives under oxidative conditions.

Keywords: H-Phosphonoselenoates; H-Phosphonates; Oxidations; Phosphoroselenothioates; Phosphorodiselenoates; Phosphorofluoridoselenoates; Oligonucleotides; Dinucleotides.

References: 30 live references.