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Collect. Czech. Chem. Commun. 2005, 70, 1465-1481

Simple Transformation of Thymine 1-[3-Hydroxy-2-(phosphonomethoxy)propyl] Derivatives to Their 1-[3-Fluoro-2-(phosphonomethoxy)propyl] Counterparts

Karel Pomeisl*, Radek Pohl, Antonín Holý and Ivan Votruba

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, CZ-166 10, Prague 6, Czech Republic

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  • Birck Matthew R., Clinch Keith, Gainsford Graeme J., Schramm Vern L., Tyler Peter C.: Syntheses of 5‐Chlorouracils/Thymines with 1‐[Phosphono(Methyl/Difluoromethyl)]‐1,2‐Unsaturated‐Moiety‐Substituted Methyl Groups at N(1) and Human Thymidine Phosphorylase Inhibitory Activity. Helvetica Chimica Acta 2009, 92, 823. <>
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