Collect. Czech. Chem. Commun. 2004, 69, 453-460
https://doi.org/10.1135/cccc20040453

Synthesis of 4,6-Disubstituted-2-(1H-indol-3-yl)benzothiazoles

Janka Záletováa, Milan Dzurillaa, Peter Kutschya,*, Pavel Pazderab, Vladimír Kováčikc, Juraj Aldölfic and Slávka Bekešovác

a Institute of Chemical Sciences, Faculty of Science, P. J. Šafárik University, Moyzesova 11, 041 67 Košice, Slovak Republic
b Department of Organic Chemistry, Faculty of Science, Masaryk University, Kotlářská 2, 611 37 Brno, Czech Republic
c Institute of Chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 842 38 Bratislava, Slovak Republic

Abstract

A new four-step synthesis of substituted 2-(1H-indol-3-yl)benzothiazoles is described, using N3-phenyl-1H-indole-3-carbothioamides as key intermediates. The structure of the obtained products was determined by IR, 1H, 13C NMR and MS spectral methods.

Keywords: Indoles; Indolylbenzothiazoles; Phytoalexins; Heterocycles; Plant hormones; Camalexin; Natural products.

References: 17 live references.