Collect. Czech. Chem. Commun. 2003, 68, 899-906

Synthesis and Structure of New Macrocyclic Bisindolylmaleimides

Christian Mandla, Manfred Zabelb and Burkhard Königa,*

a Institute of Organic Chemistry, University of Regensburg, 93040 Regensburg, Germany
b Analytical Department of NWF IV, University of Regensburg, 93040 Regensburg, Germany


We report synthesis and structure of three new macrocyclic bisindolylmaleimides. The UV spectra of the xylene-bridged compounds 4 and 6 show significant differences. A dependence of the absorption properties on the maleimide-indole torsion angles is likely. A first attempt to use induced changes in ring conformation of the more flexible macrocyclic crown ether derivative 8 to signal the presence of metal cations failed.

Keywords: Alkaloids; Arcyriarubine A; Indoles; Maleimides; Macrocycles; UV spectroscopy; X-Ray diffraction.

References: 15 live references.