Collect. Czech. Chem. Commun. 2003, 68, 812-822

Macroporous Hydrogels Based on 2-Hydroxyethyl Methacrylate. Part 1. Copolymers of 2-Hydroxyethyl Methacrylate with Methacrylic Acid

Martin Přádnýa,b,*, Petr Lesnýb,c, Jindřich Fialab,c, Jiří Vacíka,b, Miroslav Šloufa,b, Jiří Micháleka,b and Eva Sykováb,c

a Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, Heyrovského nám. 2, 162 06 Prague 6, Czech Republic
b Centre for Cell Therapy and Tissue Repair, Charles University, V Úvalu 84, 150 06 Prague 5, Czech Republic
c Institute for Experimental Medicine, Academy of Sciences of the Czech Republic, Vídeňská 1083, 142 20 Prague 4, Czech Republic


A series of macroporous crosslinked copolymers of 2-hydroxyethyl methacrylate (HEMA) with methacrylic acid (MA) was prepared in the presence of fractionated particles of sodium chloride. The hydrogels were characterized by the number of pores in unit volume, the pore size, the water content in pores and diffusion parameters. The structure of the hydrogels was followed by confocal and scanning electron microscopy.

Keywords: Diffusion; Hydrogels; 2-Hydroxyethyl methacrylate; Macroporous polymers; Morphology; Polyanions; Gels.

References: 13 live references.