Collect. Czech. Chem. Commun. 2002, 67, 1247-1261

The Stereoselective Preparation of Fluorinated Dienes via Stille-Liebeskind Cross-Coupling Reactions

Xin Zhang, Long Lu and Donald J. Burton*

Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, U.S.A.


Readily prepared fluorinated vinylstannane reagents stereoselectively undergo Stille-Liebeskind cross-coupling reactions with vinyl halides (including fluorine-containing vinyl halides) with Pd(PPh3)4/CuI catalysis.

Keywords: Cross-coupling reactions; Fluorinated dienes; Stille-Liebeskind; Fluorinated vinylstannanes; Pd(0) catalysis; Alkenes; Stannanes.

References: 25 live references.