Collect. Czech. Chem. Commun.
2002, 67, 1820-1832
https://doi.org/10.1135/cccc20021820
Synthesis and QSAR Studies of New Conjugated Benzothiazole Derivatives
Radovan Buffa, Pavol Zahradník* and Pavlína Foltínová
Faculty of Natural Sciences, Comenius University, 84135 Bratislava, Slovak Republic
Abstract
A series of new push-pull 2-(ω-phenylalkenyl)benzothiazolium compounds with methyl groups in different positions of the conjugated alkenyl bridge were synthesized by alkylation and condensation. The antimicrobial testing has been carried out and the effect of the alkenyl substituent was investigated by the QSAR Free-Wilson method.
Keywords: Benzothiazolium salts; Push-pull systems; Antimicrobial activity; Free-Wilson method; Benzothiazoles; Alkenes; Dienes; Substituent effects.
References: 15 live references.
