Collect. Czech. Chem. Commun.
2002, 67, 115-123
https://doi.org/10.1135/cccc20020115
Bioactive Flavanones from Luma chequen
Cecilia Labbéa, Josep Collb, Joseph D. Connollyc,*, Francesca Fainia, Louis J. Farrugiac and David S. Rycroftc
a Departamento de Quimica, Universidad de Chile, Casilla 653, Santiago, Chile
b IIQAB-CSIC, Jordi Girona 18-26, Barcelona, Spain
c Department of Chemistry, University of Glasgow, Glasgow G12 8QQ, Scotland, U.K.
Abstract
A bioassay-guided chemical study of a methanolic extract of fresh leaves of Luma chequen led to the isolation of lumaflavanones A (1), B (2) and C (3) whose structures are proposed on the basis of NMR spectroscopic data. The structure of lumaflavanone A was confirmed by X-ray analysis. Antifeedant (Spodoptera littoralis), brine shrimp (Artemia salina) and fungistatic (Botrytis cinerea) bioassays showed that while 3 was the most active in the first two assays the mixture of 1 and 2 was more effective as a fungistatic.
Keywords: Natural products; Flavanoids; NMR spectroscopy; Myrtaceae; Antifungal action; Antifeedant; Isolation and identification; X-Ray diffraction.
References: 13 live references.
