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Collect. Czech. Chem. Commun. 2001, 66, 483-499
https://doi.org/10.1135/cccc20010483

Cytostatic 6-Arylpurine Nucleosides III. Synthesis and Structure-Activity Relationship Study in Cytostatic Activity of 6-Aryl-, 6-Hetaryl- and 6-Benzylpurine Ribonucleosides

Michal Hoceka,*, Antonín Holýa, Ivan Votrubaa and Hana Dvořákováb

a Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, CZ-166 10 Prague 6, Czech Republic
b Laboratory of NMR Spectroscopy, Institute of Chemical Technology, Prague, CZ-166 28 Prague 6, Czech Republic

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  • Hocek Michal, Votruba Ivan, Dvořáková Hana: Synthesis of carba-analogues of myoseverin by regioselective cross-coupling reactions of 2,6-dichloro-9-isopropylpurine. Tetrahedron 2003, 59, 607. <https://doi.org/10.1016/S0040-4020(02)01586-7>
  • Turek Pavel, Kotora Martin, Hocek Michal, Cı́sařová Ivana: [2+2+2]-Co-cyclotrimerization 6-alkynylpurines with diynes: a method for preparation of 6-arylpurines. Tetrahetron Lett 2003, 44, 785. <https://doi.org/10.1016/S0040-4039(02)02643-6>
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  • Havelková Martina, Dvořák Dalimil, Hocek Michal: Covalent analogues of DNA base-pairs and triplets. Part 3: Synthesis of 1,4- and 1,3-bis(purin-6-yl)benzenes and 1-(1,3-dimethyluracil-5-yl)-3 or 4-(purin-9-yl)benzenes. Tetrahedron 2002, 58, 7431. <https://doi.org/10.1016/S0040-4020(02)00833-5>
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  • Hocek Michal, Votruba Ivan: Covalent analogues of DNA base-Pairs and triplets. Part 2: † †For Part I, see ref 1. Synthesis and cytostatic activity of bis(purin-6-yl)acetylenes,-diacetylenes and related compounds. Bioorganic & Medicinal Chemistry Letters 2002, 12, 1055. <https://doi.org/10.1016/S0960-894X(02)00077-X>
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  • Hocek Michal, Holý Antonín, Dvořáková Hana: Cytostatic 6-Arylpurine Nucleosides IV. Synthesis of 2-Substituted 6-Phenylpurine Ribonucleosides. Collect. Czech. Chem. Commun. 2002, 67, 325. <https://doi.org/10.1135/cccc20020325>
  • Hocek Michal, Stará Irena G., Starý Ivo, Dvořáková Hana: Covalent Analogues of DNA Base-Pairs and Triplets IV. Synthesis of Trisubstituted Benzenes Bearing Purine and/or Pyrimidine Rings by Cyclotrimerization of 6-Ethynylpurines and/or 5-Ethynyl-1,3-dimethyluracil. Collect. Czech. Chem. Commun. 2002, 67, 1223. <https://doi.org/10.1135/cccc20021223>
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