Collect. Czech. Chem. Commun. 2001, 66, 1691-1697
https://doi.org/10.1135/cccc20011691

Utilisation of 6-Amino-2,3-dimethylquinoxaline for the Synthesis of Tricyclic Pyridoquinoxalines via Gould-Jacobs Reaction

Jozef Saloňa, Viktor Milataa,*, Nadežda Prónayováb and Ján Leškob

a Department of Organic Chemistry, Faculty of Chemical Technology, Slovak University of Technology, 812 37 Bratislava, Slovak Republic
b Central Laboratory of Chemical Technique, Faculty of Chemical Technology, Slovak University of Technology, 812 37 Bratislava, Slovak Republic

Abstract

Treatment of 2,3-dimethylquinoxalin-6-amine with (alkoxymethylidene)malonic derivatives gave the corresponding (quinoxalylamino)ethenes, which on heating cyclized to angularly annelated pyrido[3,2-f]quinoxalin-10-ones.

Keywords: Fused heterocycles; Quinoxalines; Enaminones; Pyridoquinoxalines; Regioselective Gould-Jacobs reaction; Cyclization.

References: 12 live references.