Collect. Czech. Chem. Commun. 2000, 65, 1329-1338

Crystal Structures of Dihydro-α-ergokryptine and Dihydro-β-ergokryptine Mesylates

Jan Čejkaa, Bohumil Kratochvíla, Alexandr Jegorovb,* and Ladislav Cvakc

a Department of Solid State Chemistry, Prague Institute of Chemical Technology, Technická 5, 166 28 Prague 6, Czech Republic
b Galena Co., Research Unit, Branišovská 31, 370 05 České Budějovice, Czech Republic
c Galena Co., R. & D., 747 70 Opava-Komárov, Czech Republic


The absolute crystal structures of two related ergot alkaloids dihydro-α-ergokryptine mesylate (1) monohydrate ethanol solvate and dihydro-β-ergokryptine mesylate (2) monohydrate methanol solvate have been determined by X-ray diffraction and compared with the published structures of dihydroergocristine mesylate (3) monohydrate and dihydroergotamine mesylate (4) monohydrate.

Keywords: Ergot alkaloids; Dihydro-α-ergokryptine; Dihydro-β-ergokryptine; X-Ray structure.

References: 35 live references.