Collect. Czech. Chem. Commun. 2000, 65, 380-384

Synthesis of 21-Hydroxy-6β,19-epoxypregn-4-ene-3,20-dione

Jaroslava Hniličková* and Ladislav Kohout

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, CZ 166 10 Prague 6, Czech Republic


21-Hydroxy-6β,19-epoxypregn-4-ene-3,20-dione was prepared from 20-oxopregn-5-en-3β-yl acetate in seven steps.

Keywords: Steroids; NMR spectroscopy, 1H; Radical functionalization; Bromohydrins.

References: 5 live references.