Collect. Czech. Chem. Commun. 1999, 64, 217-228

Antitumor Agents. 192. Antitubulin Effect and Cytotoxicity of C(7)-Oxygenated Allocolchicinoids

Jian Guana, Xiao-Kang Zhua, Arnold Brossia, Yoko Tachibanaa, Kenneth F. Bastowa, Pascal Verdier-Pinardb, Ernest Hamelb, Andrew T. McPhailc and Kuo-Hsiung Leea,*

a Natural Products Laboratory, Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, U.S.A.
b Laboratory of Drug Discovery Research and Development, Development Therapeutics Program, Division of Cancer Treatment, Diagnosis and Centers, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, MD 21702, U.S.A.
c Paul M. Gross Chemical Laboratory, Duke University, Durham, NC 27708; U.S.A.

Individual author index pages

Other CCCC articles of these authors

  • Richard Friary, Andrew T. McPhail and Vera Seidl
    Novel Syntheses of Tricyclic, N-Aryl, Pyridine- and Pyrazine-Fused Pyrimidones
    1993, Vol. 58, Issue 5, pp. 1133–1150 [Abstract]
  • Anjum Muzaffar, Ernest Hamel, Rouli Bai and Arnold Brossi
    Synthesis and tubulin interaction of thiocolchicines containing an isothiocyanato group. Synthesis of C(2)-deuterated and C(2)-14C-labeled 7-isothiocyanatodeacetamidothiocolchicine
    1991, Vol. 56, Issue 11, pp. 2306–2312 [Abstract]