Collect. Czech. Chem. Commun. 1999, 64, 217-228

Antitumor Agents. 192. Antitubulin Effect and Cytotoxicity of C(7)-Oxygenated Allocolchicinoids

Jian Guana, Xiao-Kang Zhua, Arnold Brossia, Yoko Tachibanaa, Kenneth F. Bastowa, Pascal Verdier-Pinardb, Ernest Hamelb, Andrew T. McPhailc and Kuo-Hsiung Leea,*

a Natural Products Laboratory, Division of Medicinal Chemistry and Natural Products, School of Pharmacy, University of North Carolina at Chapel Hill, NC 27599, U.S.A.
b Laboratory of Drug Discovery Research and Development, Development Therapeutics Program, Division of Cancer Treatment, Diagnosis and Centers, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, MD 21702, U.S.A.
c Paul M. Gross Chemical Laboratory, Duke University, Durham, NC 27708; U.S.A.

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