Collect. Czech. Chem. Commun. 1998, 63, 990-994

NMR Study of the Structures of Ni(II) Complexes of Schiff Bases of 2-Bromoglycine with (S)-2-[(N-Benzylprolyl)amino]benzophenone or (S)-2-[(N-Benzylprolyl)amino]-5-chlorobenzophenone

Alexander Popkova, Josef Jirmanb, Milan Nádvorníkc and Petr A. Manorikd

a Positron Emission Tomography Centre, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus C, Denmark
b Research Institute for Pharmacy and Biochemistry, 533 51 Pardubice-Rosice, Czech Republic
c Department of General and Inorganic Chemistry, Faculty of Chemical Technology, University of Pardubice, 532 10 Pardubice, Czech Republic
d Institute of Physical Chemistry, National Academy of Sciences of Ukraine, pr. Nauki 31,252039 Kiev, Ukraine


The structure of a hydrolytically unstable Ni(II) complex of Schiff base of 3a with 2-bromoglycine was confirmed by NMR and 252Cf plasma desorption mass spectrometry; a new more hydrolytically stable chloro derivate 4a was prepared and investigated by 2D NMR.

Keywords: Amino acids; 252Cf Plasma desorption mass spectrometry; Nickel; NMR spectroscopy; Schiff bases.