Collect. Czech. Chem. Commun. 1998, 63, 534-540
https://doi.org/10.1135/cccc19980534

Novel Amphiphilic Cyclodextrins: Per[6-deoxy-6-(4,5-dicarboxy-1,2,3-triazol-1-yl)-2,3-di-O-methyl] Derivatives

Tomáš Kraus, Miloš Buděšínský and Jiří Závada

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic,166 10 Prague 6, Czech Republic

Abstract

Per[6-deoxy-6-(4,5-dicarboxy-1,2,3-triazol-1-yl)-2,3-di-O-methyl] substituted α- and β-cyclodextrins 6a and 6b were prepared by 1,3-dipolar cycloaddition reaction of the corresponding per(6-azido-6-deoxy-2,3-di-O-methyl)cyclodextrins 4a and 4b with dimethyl acetylenedicarboxylate.

Keywords: α-Cyclodextrin; β-Cyclodextrin; Per-carboxy cyclodextrins; 1,3-Dipolar cycloaddition; 1,2,3-Triazoles.