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Collect. Czech. Chem. Commun. 1998, 63, 441-448

High Conformational Stability of Cytochrome P-450 1A2. Evidence from UV Absorption Spectra

Pavel Anzenbachera, Nicole Becb, Jiří Hudečekc, Reinhard Langeb and Eva Anzenbacherováa

a Institute of Experimental Biopharmaceutics, Academy of Sciences of the Czech Republic - PRO.MED.CS Praha a.s., Heyrovského 1207, 500 02 Hradec Králové, Czech Republic
b INSERM Unite 128, Route de Mende 1919, 34233 Montpellier Cedex 5, France
c Department of Biochemistry, Faculty of Science, Charles University, 128 40 Prague 2, Czech Republic

Crossref Cited-by Linking

  • Davydov Dmitri R., Davydova Nadezhda Y., Halpert James R.: Allosteric Transitions in Cytochrome P450eryF Explored with Pressure-Perturbation Spectroscopy, Lifetime FRET, and a Novel Fluorescent Substrate, Fluorol-7GA. Biochemistry 2008, 47, 11348. <>
  • Davydov Dmitri R, Halpert James R, Renaud Jean-Paul, Hui Bon Hoa Gaston: Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy. Biochemical and Biophysical Research Communications 2003, 312, 121. <>
  • Lange Reinhard, Balny Claude: UV-visible derivative spectroscopy under high pressure. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology 2002, 1595, 80. <>
  • Anzenbacher Pavel, Hudeček Jiřı́: Differences in flexibility of active sites of cytochromes P450 probed by resonance Raman and UV–Vis absorption spectroscopy. Journal of Inorganic Biochemistry 2001, 87, 209. <>
  • Davydov Dmitri R., Petushkova Natalia A., Archakov Alexander I., Hoa Gaston Hui Bon: Stabilization of P450 2B4 by Its Association with P450 1A2 Revealed by High-Pressure Spectroscopy. Biochemical and Biophysical Research Communications 2000, 276, 1005. <>
  • Anzenbacherová Eva, Bec Nicole, Anzenbacher Pavel, Hudeček Jiří, Souček Pavel, Jung Christiane, Munro Andrew W., Lange Reinhard: Flexibility and stability of the structure of cytochromes P450 3A4 and BM‐3. European Journal of Biochemistry 2000, 267, 2916. <>