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Collect. Czech. Chem. Commun. 1998, 63, 2065-2074
https://doi.org/10.1135/cccc19982065

Synthesis of Acyclic Nucleotide Analogues Derived from 6-(sec- or tert-Alkyl)purines via Coupling of 6-Chloropurine Derivatives with Organocuprates

Hana Dvořákováa, Dalimil Dvořákb and Antonín Holýa

a Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic
b Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6, Czech Republic

Crossref Cited-by Linking

  • Dvorakova Hana, Dvorak Dalimil, Holy Antonin: ChemInform Abstract: Synthesis of Acyclic Nucleotide Analogues Derived from 6-(sec- or tert-Alkyl)purines via Coupling of 6-Chloropurine Derivatives with Organocuprates. ChemInform 2010, 30, no. <https://doi.org/10.1002/chin.199918207>
  • Hassan Abdalla E. A., Parker William B., Allan Paula W., Secrist John A.: Regioselective Metalation of 6-Methylpurines: Synthesis of Fluoromethyl Purines and Related Nucleosides for Suicide Gene Therapy of Cancer. Nucleosides, Nucleotides & Nucleic Acids 2009, 28, 642. <https://doi.org/10.1080/15257770903091938>
  • Kuchař Martin, Pohl Radek, Klepetářová Blanka, Votruba Ivan, Hocek Michal: Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations. Org. Biomol. Chem. 2008, 6, 2377. <https://doi.org/10.1039/b802833h>
  • Itoh Takahiro, Sato Kimihiko, Mase Toshiaki: A Novel Practical Synthesis ofC-2-Arylpurines. Adv. Synth. Catal. 2004, 346, 1859. <https://doi.org/10.1002/adsc.200404159>
  • Hocek Michal: Syntheses of Purines Bearing Carbon Substituents in Positions 2, 6 or 8 by Metal‐ or Organometal‐Mediated C−C Bond‐Forming Reactions. Eur. J. Org. Chem. 2003, 2003, 245. <https://doi.org/10.1002/ejoc.200390025>
  • Hocek Michal, Dvořáková Hana: An Efficient Synthesis of 2-Substituted 6-Methylpurine Bases and Nucleosides by Fe- or Pd-Catalyzed Cross-Coupling Reactions of 2,6-Dichloropurines. J. Org. Chem. 2003, 68, 5773. <https://doi.org/10.1021/jo034351i>
  • Česnek Michal, Hocek Michal, Holý Antonín: Synthesis of Acyclic Nucleotide Analogues Derived from 2-Amino-6-C-substituted Purines via Cross-Coupling Reactions of 2-Amino-9-{2-[(diisopropoxyphosphoryl)methoxy]ethyl}-6-halopurines with Diverse Organometallic Reagents. Collect. Czech. Chem. Commun. 2000, 65, 1357. <https://doi.org/10.1135/cccc20001357>