Collect. Czech. Chem. Commun. 1998, 63, 1646-1654

The Preparation of Some 13α-Androstanes

James R. Hanson, A. Christy Hunter and Sandrine Roquier

School of Chemistry, Physics and Environmental Science, University of Sussex, Brighton, Sussex, BN1 9QJ, England


The preparation of 17a-oxa-5α,13α-androstane-3,17-dione, 5α,13α-androstane-3,7,17-trione, 4-chloro- and 4-hydroxy-13α-androst-4-ene-3,17-dione and 13α-androst-4-ene-3,6,17-trione is described.

Keywords: Steroids; Steroidal lactones; 13α-Androstanes; 13C NMR spectroscopy; Aromatase inhibitors.