Collect. Czech. Chem. Commun. 1996, 61, 941-945

Synthesis of 3-(6-Azauracil-5-yl)anthranilic Acid and Its Application to the Preparation of Other 1,2,4-Triazine Derivatives

Jan Hlaváč and Jan Slouka

Department of Analytical and Organic Chemistry, Palacký University, 771 46 Olomouc, Czech Republic


The title compound was synthesized by alkaline recyclization of isatin-7-carboxylic acid semicarbazone and used for the preparation of 3-oxo-2,3-dihydro-5H-1,2,4-triazino[5,6-b]indol-6-carboxylic acid (8) and 3-oxo-2,3,4,6-tetrahydro-1,2,4-triazino[5,6-c]cinnoline-7-carboxylic acid (9).

Keywords: 1,2,4-Triazines.