Collect. Czech. Chem. Commun.
1996, 61, 770-773
https://doi.org/10.1135/cccc19960770
Sterically Crowded Heterocycles. V. Incorporation of Melamine and Adenine Moieties into Imidazo[1,2]heteroaromatic Molecules
Richard Kubík and Josef Kuthan
Department of Organic Chemistry, Prague Institute of Chemical Technology, 166 28 Prague 6, Czech Republic
This article is part of serial Sterically crowded heterocycles.
Abstract
Melamine and adenine react with 2,4,6-triphenylpyrylium perchlorate to corresponding quaternary pyridinium salts 1 and 2, respectively. Ferricyanide oxidation of salt 1 in alkaline medium gave (Z)-3-(2,4-diamino-7-phenylimidazo[1,2-a][1,3,5]triazin-6-yl]-1,3-diphenylprop-2-en-1-one (3). Analogous oxidation of perchlorate 2 afforded (Z)-3-(8-phenylimidazo[1,2-f]-4H-purin-7-yl)-1,3-diphenylprop-2-en-1-one (5).
Keywords: Ferricyanide oxidation; Sterically crowded heterocycles.
