Collect. Czech. Chem. Commun. 1996, 61, 427-431
https://doi.org/10.1135/cccc19960427

Synthesis of Guanosine-3'-(5-bromo-4-chloroindol-3-yl)p-hosphate (G-3'-BCIP)

Abdelfattah Haikal

Institute voor Moleculaire Biologie, Vrije Universiteit Brussel, Paardenstraat 65, Sint-Genesius-Rode, Belgium

Abstract

N-2-Benzoyl-5'-O-dimethoxytrityl-2'-O-tetrahydropyranylguanosine (5) and 1-acetyl-5-bromo-4-chloroindol-3-yl-3-phosphorodichloridate (7) were synthesized and coupled to give the title compound 9.

Keywords: Identification of ribonuclease activity.