Collect. Czech. Chem. Commun. 1995, 60, 990-998

1H, 13C, and 15N NMR Spectra of Ni(II) Complexes of Schiff Bases of (S)-2-(N-Benzylprolyl)aminobenzophenone and α-Monosubstituted Glycine and Determination of Configuration of the Complexes by 2D NOESY Spectra

Josef Jirmana and Alexander Popkovb

a Research Institute of Organic Syntheses, Joint-Stock Company, 532 18 Pardubice-Rybitví, Czech Republic
b P.O.Box 16, Zugres, Donetsk Region, 343710 Ukraine


1H, 13C, and 15N NMR spectra have been measured of substituted Ni(II) complexes of Schiff bases of (S)-2-(N-benzylprolyl)aminobenzophenone and glycine. The absolute configuration at C19 of the substituted glycine can be determined from 2D NOESY spectra using the NOESY interactions with the proton of the second chiral centre of the complex. It is possible to determine the rate of rotation of phenyl group of benzophenone unless its rotation is prevented by requatorialr orientation of dimethylamino group as it is the case with the Ni(II) complex of Schiff base of (S)-2-(N-benzylprolyl)aminobenzophenone and (S)-α-dimethylaminoglycine.