Collect. Czech. Chem. Commun. 1995, 60, 594-604
https://doi.org/10.1135/cccc19950594

Michael-Michael Aldol Reaction of Chalcones with Cyanoacetylurea and Cyanoacetylpiperidine

Hani D. Tabba, Nidal M. Yousef and Mohammad M. Al-Arab

Department of Chemistry, Yarmouk University, Irbid, Jordan

Abstract

Several highly substituted cyclohexane derivatives were synthesized by the one-pot condensation of chalcones and cyanoacetylurea (2 : 1) using sodium alkoxide in anhydrous alcohol at room temperature. The structure of the reaction products was established by infrared, 1H and 13C NMR spectroscopy as well as by their elemental analysis. Single crystal X-ray crystallography shows the presence of the cyclohexane moiety.