Collect. Czech. Chem. Commun. 1995, 60, 2147-2155

Synthesis of a Scaffold for the Creation of Non-Peptide Libraries

Alexander Kasal, Ladislav Kohout and Michal Lebl

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic


5β-Cholanic acid derivative XVII was prepared as a skeleton for the creation of non-peptide libraries. In positions 3, 7 and 12, different functional groups were designed in order to provide for the attachment of various building blocks linked to them.