Collect. Czech. Chem. Commun. 1994, 59, 1219-1225
https://doi.org/10.1135/cccc19941219

7-Oxo-7a-oxa-brassinosteroids with Cholestane Side-Chain

Ladislav Kohout

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic

Abstract

New 7-oxo-7a-oxa analogs of brassinolide with cholestane side-chain were prepared. Analogs VIII and IX with 2,3-diol grouping exhibit a weak brassinolide activity. Of the synthesized compounds, the highest brassinolide activity was found for 3α,4α-dihydroxy-7a-oxa-B-homo-5α-cholestan-7-one (X).