Collect. Czech. Chem. Commun. 1994, 59, 978-986

Synthesis of Some 2-(Substituted thio)pyridines and Thieno[2,3-b]pyridines

Maisa I. Abdel-Monem

Department of Chemistry, Faculty of Science, Assiut University, Assiut 71516, Egypt


Pyridine heterocycles occupy a unique position in medicinal chemistry. The naturally occurring B6 vitamine (pyridoxol, pyridoxal, pyridoxamine), some alkaloids and coenzymes contain pyridine nucleus. Many thienopyridine derivatives have been investigated because of the various biological activities such as against diabetes mellitus, as analgetics, anti-inflammatories, sedatives, and anticoagulants.