Collect. Czech. Chem. Commun. 1994, 59, 569-574

Separation and Determination of Some Aromatic Sulfones by Reversed-Phase High-Performance Liquid Chromatography

Josef Královskýa, Marta Kalhousováb and Petr Šlosarc

a Department of Analytical Chemistry, University of Chemical Technology, 532 10 Pardubice, Czech Republic
b Synthesia - East Bohemia Chemical Works, 532 17 Pardubice-Semtín, Czech Republic
c Research Institute of Organic Syntheses, 532 18 Pardubice-Rybitví, Czech Republic


The reversed-phase high-performance liquid chromatography of some selected, industrially important aromatic sulfones has been investigated. The chromatographic behaviour of three groups of aromatic sulfones has been studied. The optimum conditions of separation and UV spectra of the sulfones and some of their hydroxy and benzyloxy derivatives are presented. The dependences of capacity factors vs methanol content in mobile phase are mentioned. The results obtained have been applied to the quantitative analysis of different technical-grade samples and isomer mixtures. For all the separation methods mentioned the concentration ranges of linear calibration curves have been determined.