Collect. Czech. Chem. Commun. 1994, 59, 243-246

Preparation of s-Triazolo[4,3-c]quinazolines

Katarína Špirková, Štefan Stankovský and Jakub Horňaček

Department of Organic Chemistry, Slovak Technical University, 812 37 Bratislava, Slovak Republic


Several biological activities have been attributed to the quinazoline and triazole derivatives. Combining two known active heterocyclic moieties, we prepared a series of 3-aryl-5-morpholino-9-chloro-s-triazolo[4,3-c]quinazolines by an oxidative cyclization of the corresponding arylhydrazones, with the hope, that the known activities might result in a novel type of activity.