Collect. Czech. Chem. Commun. 1994, 59, 186-194

Cinnamoylacetonitrile Arylhydrazones in Heterocyclic Synthesis: Simple Synthesis of Pyridazines and their Condensed Derivatives

Galal A. M. Nawwar, Randa H. Swellem and Laila M. Chabaka

National Research Centre, Dokki, Cairo, Egypt


A new route for the synthesis of the title ring systems starting with the cinnamoylacetonitrile arylhydrazones (Ia, Ib) is described. It involves the self-cyclization of I which was found to be pH dependent.