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Collect. Czech. Chem. Commun. 1993, 58, 2159-2179

[5-(Adenin-9-yl)-5-deoxypentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. I. Derivatives with L-arabino, D-arabino, 2-Deoxy-L-erythro and 2-Deoxy-L-threo Configuration

Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic

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  • Poláková Ivana, Buděšínský Miloš, Točík Zdeněk, Rosenberg Ivan: Tetrofuranose nucleoside phosphonic acids: Synthesis and properties. Collect. Czech. Chem. Commun. 2011, 76, 503. <>
  • Králíková Šárka, Buděšínský Miloš, Tomečková Ivana, Rosenberg Ivan: Oxidative cleavage of ribofuranose 5-(α-hydroxyphosphonates): a route to erythrofuranose-based nucleoside phosphonic acids. Tetrahedron 2006, 62, 9742. <>
  • Moravcova Jitka, Heissigerova Helena, Kocalka Petr, Imberty Anne, Sykora David, Fris Miroslav: A novel seven-membered carbohydrate phostone. Tetrahedron Letters 2003, 44, 8797. <>
  • Králíková Šárka, Masojídková Milena, Buděšínský Miloš, Rosenberg Ivan: Study on Reactivity and Protection of the α-Hydroxyphosphonate Moiety in 5′-Nucleotide Analogues: Formation of the 3′-O-P-C(OH)-C4′ Internucleotide Linkage. Nucleosides, Nucleotides and Nucleic Acids 2003, 22, 329. <>
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  • Nguyen-ba N., Chan L., Quimpère M., Turcotte N., Lee N., Mitchell H., Bédard J.: Design and SAR Study of a Novel Class of Nucleotide Analogues as Potent Anti-HCMV Agents. Nucleosides and Nucleotides 1999, 18, 821. <>
  • Nguyen-Ba Paul, Turcotte Nathalie, Yuen Leonard, Bédard Jean, Quimpère Miguel, Chan Laval: Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity. Bioorganic & Medicinal Chemistry Letters 1998, 8, 3561. <>
  • Mitchell Michael C., Kee Terence P.: Recent developments in phosphono-transfer chemistry. Coordination Chemistry Reviews 1997, 158, 359. <>
  • OTMAR M., ROSENBERG I., MASOJIDKOVA M., HOLY A.: ChemInform Abstract: (5‐(Adenin‐9‐yl)‐5‐deoxypentofuranosyl)phosphonates ‐ A Novel Type of Nucleotide Analogues Related to HPMPA. Part 1. Derivatives with L‐ arabino, D‐arabino, 2‐Deoxy‐L‐erythro and 2‐Deoxy‐L‐threo Configuration. ChemInform 1994, 25. <>