Collect. Czech. Chem. Commun. 1993, 58, 2150-2158

Preparation and Characterization of Mixed Anhydrides of O-Acylarylcarbohydroximic Acid

Rajinder P. Sharma, Kusum Sharma, Sunita Lakhanpal, Namita Sharma and Bhupendra N. Misra

Department of Chemistry, Himachal Pradesh University, Summer Hill, Shimla 171 005, India


A number of N,O-diacylhydroxylamines have been prepared by the reaction of potassium salts of hydroxamic acids with variety of acylating agents which include: benzoyl, p-nitrobenzoyl, anisoyl, p-chlorobenzyl and lauroyl chlorides in dioxane under reflux. The structure of resulting N,O-diacylhydroxylamines has been determined by spectral analysis, Attempted have been made to prepare mixed anhydrides of several N,O-diacylhydroxylamines by the acylation reaction in the cold (below 10 °C) using acetyl, benzoyl, p-nitrobenzoyl, anisoyl and p-toluensulfonyl chlorides as acylating agents in dioxane using triethylamine as a base. Structures of the resulting mixed anhydrides have been elucidated by spectral methods.