Collect. Czech. Chem. Commun. 1993, 58, 1191-1194

Synthesis of Some New Type of Naphthothiazole Triazoles from Lawsone

Vedula Rajeswar Rao, Vedula M. Sharma and Tadepally V. Padmanabha Rao

Department of Chemistry, Kakatiya University, Warangal 506009, India


A series of 3-aryl naphto[2',3':4,5]thiazolo[3,2-b-1,2,4-triazolo-5,10-diones (V) have been prepared by the condensation of bromo lawsone (I) with 5-mercapto-3-substituted 1,2,4-triazole (II) followed by cyclization of the resulting uncyclized products (IV) with alkohol and sulfuric acid. The products are identical with the condensation products of 2,3-dichloro naphthoquinone (III) with 5-mercapto-3-substituted 1,2,4-triazoles in the presence of anhydrous alcohol containing fused sodium acetate.