Collect. Czech. Chem. Commun. 1993, 58, 909-917

Crystal Structure of the Native Sesquiterpene Lactone Arctolide

Urszula Rychłewskaa, Beata Szczepanskaa, Miloš Buděšínskýb, David Šamanb, Soňa Vašíčkováb, Bohdan Drożdżc, Halina Grabarczykc and Miroslav Holubb

a Department of Crystallography, Adam Mickiewicz University, Poznań, Poland
b Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic
c Department of Medicinal Plants, Academy of Medicine, Poznań, Poland


X-Ray structure analysis of the native sesquiterpenic arctolide (I) was performed. The results gave evidence that the relative configuration of the hydroxy group at C(3) in the initially suggested arctolide formula (II) has to be corrected to β. Related to this modification, formulas of some other native lactones and derivatives which had been corelated with arctolide before were also corrected.