Collect. Czech. Chem. Commun. 1993, 58, 452-454

Preparation of Some 6-Substituted N-Pyrazinyl-2-pyrazinecarboxamides

Karel Dlabal, Martin Doležal and Miloš Macháček

Faculty of Pharmacy, Charles University, 501 65, Hradec Králové, Czech Republic


In connection with our research into antimycobacterial pyrazine derivatives we were interested in binuclear analogues with -CONH- bridge. The prepared compounds were tested in the form of dimethylsulfoxide solutions for their activity against Mycobacterium tuberculosis, M. kansasii, M. avium and M. fortuitum on a liquid Sula medium (pH 5.4).