Collect. Czech. Chem. Commun.
1993, 58, 452-454
https://doi.org/10.1135/cccc19930452
Preparation of Some 6-Substituted N-Pyrazinyl-2-pyrazinecarboxamides
Karel Dlabal, Martin Doležal and Miloš Macháček
Faculty of Pharmacy, Charles University, 501 65, Hradec Králové, Czech Republic
Abstract
In connection with our research into antimycobacterial pyrazine derivatives we were interested in binuclear analogues with -CONH- bridge. The prepared compounds were tested in the form of dimethylsulfoxide solutions for their activity against Mycobacterium tuberculosis, M. kansasii, M. avium and M. fortuitum on a liquid Sula medium (pH 5.4).