Collect. Czech. Chem. Commun. 1993, 58, 3014-3016

Synthesis of 5-Arylidene-2,4,6(1H,3H,5H)pyrimidinetrione Derivatives

Josef Prousek

Department of Environmental Sciences, Laboratory of Organic Chemistry, Slovak Technical University, 812 37 Bratislava, Slovak Republic


From the synthetic viewpoint, barbituric acid and its derivatives serve in preparation of acrylidine condensation products. We have now synthesized new derivatives by reaction of barbituric acid with the corresponding heterocyclic aldehydes RCH=O in DMF.