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Collect. Czech. Chem. Commun. 1992, 57, 1960-1966
https://doi.org/10.1135/cccc19921960

Acylation of the N-Terminus of B2 Bradykinin Antagonists with Bulky Substituents Dramatically Increases Potency

Bernard Lammeka, Yasushi Itob, Irene Gavrasb and Haralambos Gavrasb

a Department of Chemistry, University of Gdańsk, Sobieskiego 18, 80-952 Gdansk, Poland
b Hypertension Section and Department of Medicine, Thorndike Memorial Laboratory, Boston City Hospital and the Department of Medicine, University Hospital, Boston University School of Medicine, U.S.A.

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  • Trzeciak Henryk I, Kozik Wojciech, Melhem Samed, Kania Aleksandra, Dobrowolski Dariusz, Prahl Adam, Derdowska Izabela, Lammek Bernard: New bradykinin analogs in contraction of rat uterus,☆. Peptides 2000, 21, 829. <https://doi.org/10.1016/S0196-9781(00)00216-3>
  • Dankwardt Sharon M., Ferla Steven, Krstenansky John L., Bhakta Sunil, Ostrelich Helene, Jarnagin Kurt: Nonpeptide bradykinin antagonist analogs based on a model of a Sterling-Winthrop nonpeptide bradykinin antagonist overlapped with cyclic hexapeptide bradykinin antagonist peptides. Bioorganic & Medicinal Chemistry Letters 1997, 7, 1921. <https://doi.org/10.1016/S0960-894X(97)00328-4>