Collect. Czech. Chem. Commun. 1992, 57, 1153-1155
https://doi.org/10.1135/cccc19921153

Base Catalyzed Condensation of Thiobarbituric Acid with Some Aromatic Aldehydes

Katarina Popov-Pergal and Miroslav Pergal

University of Novi Sad, Faculty of Science, Institute of Chemistry, Trg Dositeja Obradovića 3, 21000 Novi Sad, Yugoslavia

Abstract

In this paper the base catalyzed condensation reaction of 2-thiobarbituric acid with some aromatic aldehydes resulting in the formation of 5-arylidene-2-thiobarbituric acids is described. The condensation reaction of 2-thiobarbituric acid was carried out with 4-methoxybenzaldehyde, 4-ethoxybenzaldehyde, 4-benzyloxybenzaldehyde, and 1-naphthaldehyde using morpholine as a catalyst.