Collect. Czech. Chem. Commun. 1992, 57, 1092-1102

Sesquiterpene Lactones of Ambrosia artemisiifolia L. and Ambrosia trifida L. Species

Ełżbieta Błoszyka, Urszula Rychłewskab, Beata Szczepanskab, Miloš Buděšínskýc, Bohdan Drożdża and Miroslav Holubc

a Department of Medical Plants, Academy of Medicine, 60-623 Poznań, Poland
b Department of Crystallography, A. Mickiewicz University, 60-180 Poznań, Poland
c Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6, Czechoslovakia


In addition to the already described peruvin (I), two further lactones, 3α-hydroxy-11αH,13-dihydrodamsin (II) and, 3α-acetoxy-11αH,13-dihydrodamsin (III), were isolated from aerial parts of species Ambrosia artemisiifolia L. The full structure of these lactones was derived from their NMR and CD spectra and the X-ray structural analysis of compound III. In the aerial part of Ambrosia trifida L. species coronopilin (V) and ivoxanthin (VI) were also identified.