Collect. Czech. Chem. Commun. 1992, 57, 573-578

Quaternary Alkaloids from Thalictrum minus subsp. elatum (JACQ.) STOY. et STEFANOV

Jiří Slavík and Leonora Slavíková

Biochemical Institute of Medical Faculty, Masaryk University, 662 43 Brno


Quaternary alkaloids berberine (chloride, 0.18%) and, after transformation into the iodides, magnoflorine (iodide, 1.06%), jatrorrhizine (iodide, 0.066%), thalphenine (iodide, 0.040%) and thalifendine (iodide, 0.021%) were isolated, after separation of the tertiary bases (0.38%) from the root of Thalictrum minus subsp. elatum (JACQ.) STOJ. et STEFANOV of Czechoslovak origin (1.8% alkaloid content). The aerial parts (0.013% alkaloids) in their quaternary fraction contain only negligible amounts of magnoflorine, berberine, and coptisine (which is the first time coptisine was found in the Thalictrum genus).