Collect. Czech. Chem. Commun. 1992, 57, 450-456

Polarographic and Voltammetric Determination of Chlorobenzene, Benzyl Chloride and Melphalan

Jiří Barek, Jaroslav Matějka and Jiří Zima

Department of Analytical Chemistry, Charles University, 128 40 Prague 2


Conditions were found for the determination of chlorobenzene and benzyl chloride in dimethylformamide and of Melphalan in ethanol-water medium (4 : 1) using tast polarography at a classical dropping mercury electrode in the concentration range 1 . 10-3 - 2 . 10-5 mol l-1. Differential pulse polarography permits the range for the determination of benzyl chloride to be extended to 1 . 10-5 - 2 . 10-6 mol l-1. The use of fast scan differential pulse voltammetry and linear scan voltammetry at a hanging mercury drop electrode did not lead to an increase in the sensitivity of the determination because of the very negative half-wave potential values and high irreversibility of the processes involved.