Collect. Czech. Chem. Commun. 1992, 57, 408-414

(-)-Mitorubrinol and Phthaldehydic Acids, New Metabolites of Penicillium vermiculatum DANG.

Bohumil Proksaa, Dušan Uhrína, Ján Fuskab and Eva Michálkovác

a Institute of Chemistry, Slovak Academy of Sciences, 842 38 Bratislava
b Department of Biochemical Technology, Slovak Technical University, 812 37 Bratislava
c Drug Research Institute, 976 13 Slovenska Lupca


Three new metabolites - (-)-mitorubrinol, 2-formyl-3,5-dihydroxy-4-methylbenzoic and 2-formyl-3,5-dihydroxy-4-hydroxymethylbenzoic acids - were isolated from the culture medium of Penicillium vermiculatum DANG. Hexane extract of the mycelium contained ergosterol and esters of fatty acids, linoleic, oleic and palmitic acids being the dominating ones.