Collect. Czech. Chem. Commun. 1992, 57, 2199-2202

Reactions of 4-Aroyl-3-chloro-6-phenylpyridazines with Some Nucleophilic Reagents, Synthesis of Some Fused Pyridazine Derivatives

M. F. Ismail, A. A. Elkhamry, F. S. Sayed, S. A. Emara and A. A. Shindy

Chemistry Department, Faculty of Science, Ain Shams University, Abbassia Cairo, A. R. Egypt


As a part of our programme directed towards the synthesis of some fused pyridazine derivatives, we reported recently a novel method for the synthesis of some 4-aroyl-6-phenylpyridazin-3(2H)-ones and 4-aroyl-3-chloro-6-phenylpyridazines as readily available starting materials for this purpose. In the present investigation the reaction of 4-aroyl-3-chloro-6-phenylpyridazines (Ia-Ic) with some nucleophiles is studied.