Collect. Czech. Chem. Commun.
1992, 57, 33-45
https://doi.org/10.1135/cccc19920033
Theoretical Interpretation of High-Performance Chromatographic Data for a Heterogeneous Series of Compounds
Vladimír Jakuš
Department of Organic Technology, Slovak Technical University, Detached Laboratory in the Research Institute for Petrochemistry, 971 04 Prievidza
Abstract
A new approach to theoretical evaluation of the Gibbs free energy of solvation was applied for estimation of retention data in high-performance liquid chromatography on reversed phases (RP-HPLC). Simple and improved models of stationary and mobile phases in RP-HPLC were employed. Statistically significant correlations between the calculated and experimental data were obtained for a heterogeneous series of twelve compounds.
