Collect. Czech. Chem. Commun. 1991, 56, 1037-1041

An approach to the synthesis of novel 11-hydroxyartemisinin derivatives

Orlin Petrov and Iliya Ognyanov*

Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria


The conversion of artemisinin (I) to the epoxide V and its use for the preparation of novel artemisinin derivatives as potential antimalarial drugs is described.