Collect. Czech. Chem. Commun.
1991, 56, 916-922
https://doi.org/10.1135/cccc19910916
Synthesis of some new heterocyclic compounds containing chromene
Ahmed A. Atallaa, Adel M. Kamal El-Deanb and Abd El-Fattah A. Harba
a Chemistry Department, Faculty of Sciences of Qena, Assiut University, Assiut, Egypt
b Chemistry Department, Faculty of Science, Assiut University, Assiut, Egypt
Abstract
2-amino-3-cyano-4H-phenyl-benzo[f]chromene (I) was reacted with formamide, acetic anhydride, and ethyl cyanoacetate to produce compounds (II-IV), respectively. Compound IV reacted with HCONH2, POCl3 and P2S5 to produce corresponding pyrimidobenzochromene (V), chloropyridobenzochromene (VI) and mercaptopyridobenzochromene (VII). Compound VII reacted with α-halocompounds to produce corresponding S-alkylated derivatives (VIIIa to VIIIc), and compound (VI) reacted with different amines to produce corresponding alkyl amino-, or aryl aminopyridobenzochromene (IXa-IXc) but in using hydrazine hydrate, pyrazolopyridobenzochromene (X) was obtained.
