Collect. Czech. Chem. Commun. 1991, 56, 436-438

Dimeric pyrroline alkaloids from Lilium candium L.

Mária Haladováa, Eva Eisenreichováa, Anna Bučkováa, Jozef Tomkoa, Dušan Uhrínb and Karel Ubikc

a Department of Pharmacognosy and Botany, Pharmaceutical Faculty, Komenský University, 832 32 Bratislava
b Chemical Center, Sloval Academy of Sciences, 842 38 Bratislava
c Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Prague 6


Dimeric compounds 5,5’-oxydi(3-methyl-3-pyrrolin-2-one) and 5-hydroxy-3-methyl-1-(3’-methyl-2’-oxo-3’-pyrrolin-2-one were isolated from bulbs of Lilium candidum L., family Liliaceae. Structure of these compounds has been confirmed by spectral measurements. The ether link between two substituted pyrroline rings represents a new type of dimeric alkaloids.